Kartagener Syndrome - Symptoms & Treatment
Kartagener's Syndrome is a chronic lung disease which occurs when cilia are incompetent to move. Kartagener's Syndrome is a rare hereditic birth defect. Individuals with Kartagener's Syndrome have unnatural or absent ciliary motion. Kartagener's Syndrome is also called Primary Ciliary Dyskinesia, and Immotile Cilia Syndrome, Afzelius' syndrome, Kartagener's triad, Zivert's syndrome, and Zivert-Kartagener triad. A genetic syndrome distinguished by sinusitis, bronchiectasis (widening and inflammation of the bronchi), dextrocardia (heart on the right side), and infertility. The syndrome is congenital in an autosomal recessive manner. Kartagener syndrome is usually because of metamorphosis in the gene called DNAI1 (axonemal dynein intermediate chain) which is in chromosome region 9p21-p13. However, hookup studies have mapped the disease gene to 5p and 19q in some families, indicating that Kartagener syndrome is more than one genetic entity.
Symptoms of Kartagener Syndrome
Some common Symptoms of Kartagener Syndrome :
- Chronic rhinitis.
- Recurrent or chronic bronchitis.
- Bronchiectasis.
- Recurrent or chronic sinusitis.
- Infertility.
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